Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11549721 | 0.95 | ALDH1A1 (0.56) | ALDH1A1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11682140 | 0.94 | ALDH1A1 (0.57) | ALDH1A1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11551498 | 0.94 | ALDH1A1 (0.57) | ALDH1A1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11669564 | 0.88 | ALDH1A1 (0.51) | ALDH1A1RAB9ASMN1; SMN2PKMKMT2A | |
| SCHEMBL11670623 | 0.83 | ALDH1A1 (0.54) | ALDH1A1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11669924 | 0.83 | ALDH1A1 (0.54) | ALDH1A1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11555476 | 0.80 | TP53 (0.51) | ALDH1A1RAB9ASMN1; SMN2PKMKMT2A | |
| SCHEMBL11553782 | 0.80 | ALDH1A1 (0.50) | ALDH1A1RAB9ASMN1; SMN2PKMKMT2A | |
| SCHEMBL11686902 | 0.79 | ALDH1A1 (0.49) | ALDH1A1RAB9ASMN1; SMN2PKMKMT2A | |
| SCHEMBL11682862 | 0.78 | ALDH1A1 (0.51) | ALDH1A1RAB9ASMN1; SMN2PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4012223-A | Thiadiazolylimidazolidinones herbicides | VELSICOL CHEMICAL CORPORATION (US) | 1977-03-15 | — | — | US | disclosed |