Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.51 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.41 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15859009 | 0.74 | IDO1 (0.54) | IDO1IMPDH2IMPDH1ENPP2MAPT | |
| SCHEMBL11361203 | 0.73 | HSD17B10 (0.36) | KDM4EPOLBHSD17B10GAACYP3A4 | |
| SCHEMBL970690 | 0.72 | IDO1 (0.56) | IDO1IMPDH2IMPDH1MAPTALPL | |
| SCHEMBL2089491 | 0.72 | IDO1 (0.45) | IDO1IMPDH2IMPDH1ENPP2MAPT | |
| SCHEMBL971690 | 0.69 | KDM4E (0.53) | KDM4EPOLBHSD17B10GAAALDH1A1 | |
| SCHEMBL11684549 | 0.69 | IDO1 (0.50) | IDO1ENPP2MAPTKDM4EPOLB | |
| SCHEMBL11683730 | 0.68 | IDO1 (1.00) | IDO1ENPP2CYP3A4ALDH1A1MAPK1 | |
| SCHEMBL3572563 | 0.68 | IDO1 (1.00) | IDO1ENPP2MAPTKDM4EHSD17B10 | |
| SCHEMBL209984 | 0.66 | NPC1 (0.56) | MAPTKDM4EPOLBHSD17B10GAA | |
| SCHEMBL29532421 | 0.66 | NPC1 (0.56) | MAPTKDM4EPOLBHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4020083-A | ANTIINFLAMMATORY | SANDOZ, INC. (US) | 1977-04-26 | — | — | US | disclosed |