SCHEMBL209984

SCHEMBL209984

COc1cc(N)c(N)cc1OC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.56
KDM4E B2RXH2 1/20 0.54
ALDH1A1 P00352 7/20 0.52
CYP3A4 P08684 5/20 0.52
TDP1 Q9NUW8 2/20 0.52
TSHR P16473 1/20 0.52
HSD17B10 Q99714 1/20 0.52
POLB P06746 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
GAA P10253 2/20 0.50
ADRA2B P18089 1/20 0.50
PTGS1 P23219 1/20 0.50
PKM P14618 1/20 0.48
MAPT P10636 2/20 0.48
MEN1 O00255 1/20 0.48
THRB P10828 1/20 0.48
KMT2A Q03164 1/20 0.48
EHMT2 Q96KQ7 1/20 0.44
PTK2 Q05397 1/20 0.44
ACHE P22303 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29532421 1.00 NPC1 (0.56) NPC1KDM4EALDH1A1CYP3A4TDP1
Hydrochloric Acid SCHEMBL546210 0.97 NPC1 (0.54) NPC1KDM4EALDH1A1CYP3A4TDP1
Hydrochloric Acid SCHEMBL5957727 0.97 NPC1 (0.54) NPC1KDM4EALDH1A1CYP3A4TDP1
Ammonia Solution, Strong SCHEMBL7757604 0.97 NPC1 (0.54) NPC1KDM4EALDH1A1CYP3A4TDP1
Benzene SCHEMBL29154358 0.94 ALDH1A1 (0.52) NPC1KDM4EALDH1A1CYP3A4TDP1
SCHEMBL1708452 0.88 GAA (0.65) NPC1KDM4EALDH1A1CYP3A4TDP1
SCHEMBL11878678 0.88 L3MBTL1 (0.61) NPC1KDM4EALDH1A1CYP3A4TDP1
SCHEMBL926329 0.87 L3MBTL1 (0.67) NPC1KDM4EALDH1A1CYP3A4TDP1
SCHEMBL17403698 0.85 ALDH1A1 (0.46) NPC1KDM4EALDH1A1CYP3A4TDP1
SCHEMBL1225409 0.83 POLB (0.61) NPC1KDM4EALDH1A1CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 401 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115926188-A Salphen-based metal organic framework material, and preparation method and application thereof 天津大学 2023-04-07 CN claimed
CN-113549082-B Polyhydroxy compound and preparation method and application thereof 广东工业大学 2022-09-09 CN claimed
CN-113549082-A Polyhydroxy compound and preparation method and application thereof 广东工业大学 2021-10-26 CN claimed
CN-109557207-A Method for quantitatively determining substrate conversion and product generation and distribution in ALS/AHAS enzyme catalytic reaction process 西北大学 2019-04-02 CN claimed
CN-108226333-A Glucose degradation products detects and controls method in a kind of Multiple electrolytes injection 青岛力腾化工医药研究有限公司 2018-06-29 CN claimed
US-20050214894-A1 High throughput assay ISIS INNOVATION LIMITED (GB) 2005-09-29 US claimed
JP-3291272-A None JP disclosed
US-12638394-B2 Skin sensitization measuring reagent, method for measuring skin sensitization, and compound FUJIFILM CORPORATION (JP) 2026-05-26 US disclosed
EP-4549472-A2 COMPOSITIONS FOR SUNSCREEN COMPOUNDS AND METHODS THEREOF PMIDG, LLC (US) 2025-05-07 EP disclosed
EP-4036570-B1 REAGENT FOR MEASURING SKIN SENSITIZATION, METHOD FOR MEASURING SKIN SENSITIZATION, AND COMPOUND FUJIFILM CORP (JP) 2025-03-05 EP disclosed
EP-4013374-B1 COMPOSITIONS FOR SUNSCREEN COMPOUNDS AND METHODS THEREOF PMIDG LLC (US) 2025-02-19 EP disclosed
CN-114276334-B Carbazole alkylation aromatic heterocyclic derivative and preparation method thereof 内蒙古民族大学 2024-04-09 CN disclosed
CN-113166156-B Tyrosine kinase inhibitors, compositions and methods 贝达药业股份有限公司 2024-02-27 CN disclosed
EP-0098448-A2 Imidazole derivatives, their preparation and medicines containing these compounds Dr. Karl Thomae GmbH (DE) 1984-01-18 EP disclosed
EP-0073456-A1 Tetraazaannulene cobalt complex compounds and method for preparation thereof Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1983-03-09 EP disclosed
US-4216320-A Quinoxaline bleach catalysts CIBA-GEIGY AG (CH) 1980-08-05 US disclosed
US-4145217-A DYE BLEACH CATALYST CIBA-GEIGY AG (CH) 1979-03-20 US disclosed
US-4138568-A NITRO-O-PHENYLENEDIAMINE, UREA, HALOBENZENE SOLVENT CIBA-GEIGY CORPORATION (US) 1979-02-06 US disclosed
US-4008225-A Process for the manufacture of bis-azomethine metal complex colorants CIBA-GEIGY CORPORATION (US) 1977-02-15 US disclosed
US-3963708-A Bis-azomethine metal complex colorants from hydroxycoumarin derivatives or hydroxychromone derivatives CIBA-GEIGY CORPORATION (US) 1976-06-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12638394-B2 Skin sensitization measuring reagent, method for measuring skin sensitization, and compound HRH1, HRH4, CUTA NPC1 3240/4885KDM4E 2626/4885ALDH1A1 425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.