SCHEMBL11683151

SCHEMBL11683151

CC(O)Oc1ccc(C=CC(=O)O)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.64
ATM Q13315 1/20 0.64
KDM4E B2RXH2 3/20 0.59
MAPK1 P28482 2/20 0.59
HCAR2 Q8TDS4 2/20 0.52
CA12 O43570 2/20 0.52
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA3 P07451 2/20 0.52
PKM P14618 2/20 0.52
CA4 P22748 2/20 0.52
CA6 P23280 2/20 0.52
CA5A P35218 2/20 0.52
CA7 P43166 2/20 0.52
CA9 Q16790 2/20 0.52
CA14 Q9ULX7 2/20 0.52
CA5B Q9Y2D0 2/20 0.52
AKR1B10 O60218 1/20 0.52
ESR1 P03372 1/20 0.52
TYR P14679 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11686591 1.00 THRB (0.64) THRBATMKDM4EMAPK1HCAR2
SCHEMBL11683362 0.90 THRB (0.51) THRBATMKDM4EMAPK1HCAR2
SCHEMBL1207345 0.88 THRB (0.66) THRBATMKDM4EMAPK1HCAR2
SCHEMBL1207346 0.88 THRB (0.66) THRBATMKDM4EMAPK1HCAR2
SCHEMBL11684640 0.83 CA12 (0.60) THRBATMKDM4ECA12CA1
SCHEMBL11681984 0.83 CA12 (0.60) THRBATMKDM4ECA12CA1
SCHEMBL7455201 0.82 THRB (0.58) THRBATMKDM4EMAPK1HCAR2
SCHEMBL3687164 0.82 THRB (0.58) THRBATMKDM4EMAPK1HCAR2
SCHEMBL4537506 0.82 THRB (0.58) THRBATMKDM4EMAPK1HCAR2
SCHEMBL3687167 0.82 THRB (0.58) THRBATMKDM4EMAPK1HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4053415-A UNSATURATED POLYESTER ETHER HAVING A PHOTOCROSSLINKABLE MOIETY FUJI PHOTO FILM CO., LTD. (JA) 1977-10-11 US disclosed