Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 8/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.48 |
| ▸ | PGR | P06401 | 6/20 | 0.48 |
| ▸ | AR | P10275 | 4/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11681635 | 0.94 | NR3C1 (0.47) | NR3C1CYP3A4HIF1APGRAR | |
| SCHEMBL11683809 | 0.94 | NR3C1 (0.47) | NR3C1CYP3A4HIF1APGRAR | |
| SCHEMBL11681918 | 0.93 | CYP3A4 (0.46) | NR3C1CYP3A4HIF1APGRAR | |
| SCHEMBL11679731 | 0.92 | NR3C1 (0.51) | NR3C1CYP3A4HIF1APGRAR | |
| SCHEMBL11680318 | 0.87 | CYP3A4 (0.46) | NR3C1CYP3A4HIF1APGRAR | |
| SCHEMBL11683109 | 0.86 | NR3C1 (0.51) | NR3C1CYP3A4HIF1APGRAR | |
| SCHEMBL11682629 | 0.85 | CYP3A4 (0.51) | NR3C1CYP3A4HIF1APGRAR | |
| SCHEMBL11686840 | 0.85 | NR3C1 (0.51) | NR3C1CYP3A4HIF1APGRAR | |
| SCHEMBL11866793 | 0.84 | CYP3A4 (0.49) | NR3C1CYP3A4HIF1APGRAR | |
| SCHEMBL11682502 | 0.84 | NR3C1 (0.58) | NR3C1CYP3A4HIF1APGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4065452-A | TOPICAL ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1977-12-27 | — | — | US | disclosed |