Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 4/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11687878 | 0.88 | ABCG2 (0.50) | MAOBMAPTLMNASMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL11688059 | 0.87 | ABCG2 (0.49) | MAOBMAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL11683231 | 0.76 | MAOB (0.50) | MAOBMAPTLMNAATMSMN1; SMN2 | |
| SCHEMBL11683229 | 0.76 | MAOB (0.50) | MAOBMAPTLMNAATMSMN1; SMN2 | |
| SCHEMBL6238514 | 0.76 | L3MBTL1 (0.44) | MAPTLMNANPC1RAB9AKMT2A | |
| SCHEMBL11686572 | 0.74 | MAOB (0.48) | MAOBMAPTKMT2AABCG2MAOA | |
| SCHEMBL11683918 | 0.74 | CYP1B1 (0.56) | MAOBMAPTKMT2AMAOACYP1A1 | |
| SCHEMBL11683074 | 0.71 | MAOB (0.49) | MAOBKMT2AABCG2MAOA | |
| SCHEMBL11684301 | 0.69 | MAOB (0.47) | MAOBABCG2MAOACYP1A1CYP1B1 | |
| SCHEMBL10933442 | 0.69 | USP2 (0.45) | MAPTLMNASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4006234-A | Substituted 2-benzofuranyl propenones as anti-tubercular agents | AMERICAN CYANAMID COMPANY (US) | 1977-02-01 | — | — | US | disclosed |
| US-3931157-A | ANTITUBERCULAR | AMERICAN CYANAMID COMPANY (US) | 1976-01-06 | — | — | US | disclosed |