SCHEMBL11684111

SCHEMBL11684111

Nc1ccc(S(=O)(=O)Nc2ccc(CS(=O)(=O)O)cc2)cc1C(F)(F)F

nearest known ligand 0.63

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 11/20 0.63
FFAR1 O14842 3/20 0.57
ERAP1 Q9NZ08 1/20 0.42
TRPV1 Q8NER1 1/20 0.41
PGR P06401 1/20 0.41
HSPD1 P10809 2/20 0.41
PTPN2 P17706 2/20 0.41
PTPN1 P18031 2/20 0.41
PTPN5 P54829 2/20 0.41
HSPE1 P61604 2/20 0.41
MAPT P10636 1/20 0.40
MEN1 O00255 1/20 0.40
ALOX15 P16050 1/20 0.40
MAPK1 P28482 1/20 0.40
KMT2A Q03164 1/20 0.40
LMNA P02545 1/20 0.40
TP53 P04637 1/20 0.40
THRB P10828 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11682697 0.88 FFAR4 (0.58) FFAR4FFAR1ERAP1MAPTMEN1
SCHEMBL11682704 0.86 FFAR4 (0.67) FFAR4FFAR1MAPTMEN1ALOX15
Methane SCHEMBL11684647 0.85 FFAR4 (0.66) FFAR4FFAR1MAPTMEN1ALOX15
SCHEMBL11518943 0.79 FFAR4 (0.64) FFAR4FFAR1ERAP1MEN1KMT2A
Methane SCHEMBL11683666 0.78 FFAR4 (0.63) FFAR4FFAR1ERAP1
SCHEMBL28537715 0.78 FFAR4 (1.00) FFAR4FFAR1MAPTKMT2A
SCHEMBL11685957 0.77 CA1 (0.61) MAPTMEN1KMT2ALMNA
SCHEMBL11683101 0.76 MAPT (0.58) FFAR4MAPTMEN1ALOX15MAPK1
SCHEMBL11518471 0.74 CYP2D6 (0.58) FFAR4FFAR1MAPTMEN1KMT2A
SCHEMBL28543669 0.73 FFAR4 (1.00) FFAR4FFAR1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4055557-A MONOAZO DYES BAYER AKTIENGESELLSCHAFT (DT) 1977-10-25 US disclosed