Methane

Methane

SCHEMBL11684647

C.Nc1ccc(S(=O)(=O)Nc2ccc(S(=O)(=O)O)cc2)cc1C(F)(F)F

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 11/20 0.66
FFAR1 O14842 3/20 0.62
MAPT P10636 3/20 0.43
MEN1 O00255 1/20 0.43
ALOX15 P16050 1/20 0.43
MAPK1 P28482 1/20 0.43
KMT2A Q03164 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
KIF11 P52732 1/20 0.43
TSHR P16473 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
LMNA P02545 1/20 0.42
TP53 P04637 1/20 0.42
THRB P10828 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11682704 0.99 FFAR4 (0.67) FFAR4FFAR1MAPTMEN1ALOX15
Methane SCHEMBL11683666 0.87 FFAR4 (0.63) FFAR4FFAR1TSHRCA1CA2
SCHEMBL11518943 0.86 FFAR4 (0.64) FFAR4FFAR1MEN1KMT2ATSHR
SCHEMBL11684111 0.85 FFAR4 (0.63) FFAR4FFAR1MAPTMEN1ALOX15
SCHEMBL11243895 0.82 FFAR4 (0.54) FFAR4FFAR1MAPTMEN1KMT2A
SCHEMBL11684222 0.80 FFAR4 (0.54) FFAR4FFAR1MAPTMEN1KMT2A
SCHEMBL11684501 0.80 FFAR4 (0.54) FFAR4FFAR1MEN1KMT2ATSHR
SCHEMBL11682697 0.78 FFAR4 (0.58) FFAR4FFAR1MAPTMEN1KMT2A
SCHEMBL10692669 0.77 MAPT (0.57) FFAR4FFAR1MAPTALOX15KMT2A
SCHEMBL11687178 0.77 MAPT (0.53) FFAR4MAPTMEN1KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4055557-A MONOAZO DYES BAYER AKTIENGESELLSCHAFT (DT) 1977-10-25 US disclosed