Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1002968 | 0.83 | NTRK1 (0.58) | NTRK1KDM4EALDH1A1HSD17B10USP2 | |
| SCHEMBL29469528 | 0.83 | NTRK1 (0.58) | NTRK1KDM4EALDH1A1HSD17B10USP2 | |
| SCHEMBL12480314 | 0.76 | PTGS2 (0.47) | NTRK1KDM4EALDH1A1ABCB1PTGS1 | |
| SCHEMBL26771824 | 0.76 | PTGS2 (0.77) | KDM4EMAPTCYP1A2CYP2C9NPSR1 | |
| SCHEMBL17102822 | 0.75 | EGFR (0.56) | MAPTCYP1A2CYP2C9NPSR1ABCB1 | |
| SCHEMBL17102845 | 0.75 | ABCB1 (0.61) | KDM4EMAPTCYP1A2CYP2C9NPSR1 | |
| SCHEMBL10820374 | 0.75 | CHRM2 (0.47) | KDM4EALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL14245254 | 0.74 | CHRM2 (0.49) | ABCB1PTGS1PTGS2POLBL3MBTL1 | |
| SCHEMBL10268206 | 0.73 | MEN1 (0.66) | NTRK1KDM4EALDH1A1MAPTCYP1A2 | |
| SCHEMBL6919765 | 0.73 | NTRK1 (0.49) | NTRK1KDM4EALDH1A1HSD17B10USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4022802-A | INDOLES, ALKALI HYDROXIDE; ALKYLATION | CIBA-GEIGY AG (CH) | 1977-05-10 | — | — | US | disclosed |
| US-3969346-A | Naphtholactamcarbinols color formers, their manufacture and use in pressure-sensitive or thermoreactive recording material | CIBA-GEIGY CORPORATION (US) | 1976-07-13 | — | — | US | disclosed |