Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TSPO | P30536 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11469036 | 0.87 | TSHR (0.51) | TSHRCYP2C19MAPTALDH1A1CNR2 | |
| SCHEMBL11682501 | 0.87 | MAPT (0.45) | TSHRCYP2C19MAPTALDH1A1POLB | |
| SCHEMBL11684138 | 0.86 | TSHR (0.50) | TSHRMAPTCNR2L3MBTL1TSPO | |
| SCHEMBL10632613 | 0.85 | MAPT (0.51) | TSHRMAPTALDH1A1POLBL3MBTL1 | |
| SCHEMBL11681710 | 0.84 | ATM (0.45) | TSHRCYP2C19MAPTALDH1A1POLB | |
| SCHEMBL11682723 | 0.81 | CNR2 (0.42) | TSHRCYP2C19MAPTALDH1A1POLB | |
| SCHEMBL11681949 | 0.79 | TSHR (0.43) | TSHRMAPTALDH1A1POLBCNR2 | |
| SCHEMBL15705233 | 0.79 | CYP2C19 (0.50) | CYP2C19MAPTALDH1A1POLBL3MBTL1 | |
| SCHEMBL18309427 | 0.75 | CYP2C19 (0.46) | TSHRCYP2C19MAPTALDH1A1CNR2 | |
| SCHEMBL11683641 | 0.74 | KDM4E (0.42) | TSHRCYP2C19MAPTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041024-A | FOR POLYAMIDES AND POLYURETHANES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-09 | — | — | US | disclosed |