Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | TSPO | P30536 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11684279 | 0.86 | TSHR (0.50) | TSHRMAPTCNR2TSPOL3MBTL1 | |
| SCHEMBL10998181 | 0.85 | NQO1 (0.46) | TSHRMAPTL3MBTL1 | |
| SCHEMBL11680442 | 0.81 | LTA4H (0.43) | TSHRMAPTCNR2LTA4HL3MBTL1 | |
| SCHEMBL11684683 | 0.81 | TSHR (0.51) | TSHRMAPTCNR2BCHEL3MBTL1 | |
| SCHEMBL11680597 | 0.81 | MEN1 (0.41) | TSHRMAPTCNR2CETPL3MBTL1 | |
| SCHEMBL11682291 | 0.79 | TSHR (0.62) | TSHRMAPTCNR2BCHECETP | |
| SCHEMBL11681949 | 0.79 | TSHR (0.43) | TSHRMAPTCNR2BCHETSPO | |
| SCHEMBL11776697 | 0.77 | CYP2C19 (0.59) | TSHRMAPTCNR2RELALTA4H | |
| SCHEMBL11342978 | 0.75 | KDM4E (0.46) | TSHRMAPT | |
| SCHEMBL3993241 | 0.74 | MAOB (0.53) | MAPTBCHEL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041024-A | FOR POLYAMIDES AND POLYURETHANES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-09 | — | — | US | disclosed |