Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TLR4 | O00206 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5454243 | 0.93 | ALDH1A1 (0.43) | GAATDP1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL5443168 | 0.88 | HPGD (0.37) | GAATDP1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL16160607 | 0.87 | ALDH1A1 (0.48) | GAATDP1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL5446680 | 0.87 | ALDH1A1 (0.36) | GAATDP1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL19710403 | 0.87 | GAA (0.48) | GAATDP1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL5444761 | 0.86 | ERN1 (0.40) | GAATDP1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL5452274 | 0.86 | EGFR (0.41) | GAATDP1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL5454088 | 0.86 | CYP1A2 (0.43) | ALDH1A1KDM4EMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL5456528 | 0.85 | ALDH1A1 (0.44) | GAATDP1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL5451522 | 0.84 | TSHR (0.46) | L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4024274-A | Benzylamine derivatives and process for preparing them | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | disclosed |