Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11774212 | 0.77 | POLB (0.59) | POLBKMT2ARAB9ASMN1; SMN2MAPT | |
| SCHEMBL10246092 | 0.76 | POLB (0.58) | POLBKMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL10304450 | 0.75 | POLB (0.62) | POLBKMT2ARAB9ASMN1; SMN2MAPT | |
| SCHEMBL18997087 | 0.75 | LMNA (0.56) | POLBKMT2ARAB9ASMN1; SMN2MAPT | |
| SCHEMBL11818700 | 0.73 | POLB (0.61) | POLBKMT2AALDH1A1LMNA | |
| SCHEMBL24980367 | 0.72 | AKR1B1 (0.63) | POLBKMT2ASMN1; SMN2ALDH1A1AKR1B1 | |
| SCHEMBL19002339 | 0.72 | LMNA (0.60) | POLBKMT2ARAB9ASMN1; SMN2MAPT | |
| SCHEMBL11808078 | 0.72 | KMT2A (0.63) | POLBKMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL14499604 | 0.71 | KMT2A (0.60) | KMT2ARAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL11638327 | 0.71 | HSD17B10 (0.57) | POLBKMT2ARAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4014824-A | HYDANTOIN DERIVATIVES, EPOXY RESINS | CIBA-GEIGY CORPORATION (US) | 1977-03-29 | — | — | US | disclosed |