Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11683793 | 1.00 | LMNA (0.56) | LMNASMN1; SMN2HTTMAPTALDH1A1 | |
| SCHEMBL11682131 | 0.94 | LMNA (0.62) | LMNASMN1; SMN2HTTMAPTALDH1A1 | |
| SCHEMBL11060178 | 0.85 | EPHX1 (0.65) | LMNAHTTMAPTALDH1A1KMT2A | |
| SCHEMBL8966845 | 0.85 | EPHX1 (0.65) | LMNAHTTMAPTALDH1A1KMT2A | |
| SCHEMBL11052534 | 0.85 | EPHX1 (0.65) | LMNAHTTMAPTALDH1A1KMT2A | |
| SCHEMBL11057865 | 0.83 | EPHX1 (0.62) | LMNAHTTMAPTALDH1A1KMT2A | |
| SCHEMBL8762360 | 0.83 | MAPT (0.50) | LMNASMN1; SMN2HTTMAPTALDH1A1 | |
| SCHEMBL8391699 | 0.80 | LMNA (0.65) | LMNASMN1; SMN2HTTMAPTALDH1A1 | |
| SCHEMBL8440594 | 0.80 | LMNA (0.65) | LMNASMN1; SMN2HTTMAPTALDH1A1 | |
| SCHEMBL8443237 | 0.80 | LMNA (0.65) | LMNASMN1; SMN2HTTMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4030925-A | Photographic compositions and elements including internal latent image silver halide grains and acylhydrazinophenylthiourea nucleating agents therefor | EASTMAN KODAK COMPANY (US) | 1977-06-21 | — | — | US | claimed |
| US-4031127-A | Acyl hydrazino thiourea derivatives as photographic nucleating agents | EASTMAN KODAK COMPANY (US) | 1977-06-21 | — | — | US | claimed |
| US-4030925-A | Photographic compositions and elements including internal latent image silver halide grains and acylhydrazinophenylthiourea nucleating agents therefor | EASTMAN KODAK COMPANY (US) | 1977-06-21 | — | — | US | disclosed |
| US-4031127-A | Acyl hydrazino thiourea derivatives as photographic nucleating agents | EASTMAN KODAK COMPANY (US) | 1977-06-21 | — | — | US | disclosed |