Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MITF | O75030 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11685414 | 0.99 | KMT2A (0.70) | KMT2AMEN1ALDH1A1KDM4EPOLB | |
| SCHEMBL19650826 | 0.93 | KMT2A (0.57) | KMT2AMEN1ALDH1A1KDM4EPOLB | |
| SCHEMBL11684508 | 0.87 | MEN1 (0.74) | KMT2AMEN1ALDH1A1KDM4EPOLB | |
| SCHEMBL11684541 | 0.87 | MEN1 (0.74) | KMT2AMEN1ALDH1A1KDM4EPOLB | |
| Hydrochloric Acid SCHEMBL11685219 | 0.85 | MEN1 (0.73) | KMT2AMEN1ALDH1A1KDM4EPOLB | |
| Hydrochloric Acid SCHEMBL11685544 | 0.85 | MEN1 (0.73) | KMT2AMEN1ALDH1A1KDM4EPOLB | |
| SCHEMBL18768922 | 0.82 | POLB (0.62) | KMT2AMEN1ALDH1A1POLBHTT | |
| SCHEMBL18768842 | 0.82 | POLB (0.62) | KMT2AMEN1ALDH1A1POLBHTT | |
| SCHEMBL18742079 | 0.82 | POLB (0.62) | KMT2AMEN1ALDH1A1POLBHTT | |
| SCHEMBL11684296 | 0.81 | ALDH1A1 (0.62) | KMT2AMEN1ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4024274-A | Benzylamine derivatives and process for preparing them | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | disclosed |