Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.67 |
| ▸ | HTR1A | P08908 | 5/20 | 0.67 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.67 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.67 |
| ▸ | DRD1 | P21728 | 5/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.67 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.67 |
| ▸ | DRD3 | P35462 | 5/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.67 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.67 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.67 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6879961 | 1.00 | CHRM2 (0.67) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL6883388 | 1.00 | CHRM2 (0.67) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL11688160 | 0.89 | ITGB2 (0.59) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL11686974 | 0.85 | CYP2D6 (0.74) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL16316914 | 0.82 | PTGS1 (0.73) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| Ammonia Solution, Strong SCHEMBL11614407 | 0.81 | PTGS1 (0.67) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL16373286 | 0.80 | CHRM2 (0.63) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| Methylpromazine SCHEMBL29354434 | 0.80 | CHRM2 (1.00) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| Methylpromazine SCHEMBL18993 | 0.80 | CHRM2 (1.00) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| Methylpromazine SCHEMBL18994 | 0.80 | CHRM2 (1.00) | CHRM2HTR1AADRA2ACHRM1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4018922-A | NEUROLEPTICS, ANALGESICS, SPASMOLYTICS, AND ANTIHISTAMINES | ROUSSEL-UCLAF (FR) | 1977-04-19 | — | — | US | disclosed |