Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL1168618

CCc1ccc(Cl)cc1Cl.N

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 5/20 0.58
MAPK1 P28482 2/20 0.56
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2C9 P11712 1/20 0.56
CYP2C19 P33261 1/20 0.56
LMNA P02545 1/20 0.50
NLRP1 Q9C000 1/20 0.50
GGPS1 O95749 1/20 0.48
TP53 P04637 1/20 0.46
HTT P42858 3/20 0.46
PYCR1 P32322 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.44
EPHX1 P07099 1/20 0.44
KDM4E B2RXH2 1/20 0.43
TDP1 Q9NUW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL155790 0.98 IDO1 (0.60) IDO1MAPK1CYP1A2CYP3A4CYP2C9
Formaldehyde SCHEMBL28039021 0.93 IDO1 (0.56) IDO1MAPK1CYP1A2CYP3A4CYP2C9
Butylamine SCHEMBL11459551 0.82 IDO1 (0.46) IDO1MAPK1CYP1A2CYP3A4CYP2C9
Acrylic Acid SCHEMBL9668105 0.81 MAPK1 (0.48) IDO1MAPK1CYP1A2CYP3A4CYP2C9
SCHEMBL12603775 0.80 AHR (0.50) IDO1MAPK1CYP1A2CYP3A4CYP2C9
SCHEMBL3782085 0.80 IDO1 (0.44) IDO1MAPK1CYP1A2CYP3A4CYP2C9
SCHEMBL426435 0.79 IDO1 (0.56) IDO1MAPK1CYP1A2CYP3A4CYP2C9
SCHEMBL257058 0.78 HTR2A (0.51) IDO1MAPK1CYP1A2CYP3A4CYP2C9
SCHEMBL1047227 0.78 IDO1 (0.60) IDO1MAPK1CYP1A2CYP3A4CYP2C9
SCHEMBL30102510 0.78 HTR2A (0.51) IDO1MAPK1CYP1A2CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11035528-A None JP disclosed
US-9175006-B2 Compositions and methods for cyclofructans as separation agents BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2015-11-03 US disclosed
US-20110024292-A1 COMPOSITIONS AND METHODS FOR CYCLOFRUCTANS AS SEPARATION AGENTS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2011-02-03 US disclosed
JP-H1135528-A PRODUCTION OF BENZYLAMINE DAICEL CHEM IND LTD 1999-02-09 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110024292-A1 COMPOSITIONS AND METHODS FOR CYCLOFRUCTANS AS SEPARATION AGENTS PAICS, DCXR, PFAS IDO1 1150/4885MAPK1 4106/4885CYP1A2 1956/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.