Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.53 |
| ▸ | MAOA | P21397 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11684301 | 0.90 | MAOB (0.47) | MAOBMAOACYP1A2CXCL12ABCG2 | |
| SCHEMBL11683585 | 0.85 | MAOB (0.58) | MAOBMAOAMAPTMEN1KMT2A | |
| SCHEMBL11684819 | 0.85 | MAOA (0.55) | MAOBMAOAMAPTMEN1KMT2A | |
| SCHEMBL11685608 | 0.85 | STAT3 (0.47) | MAOBMAOAMAPTPOLBMEN1 | |
| SCHEMBL11687556 | 0.84 | CYP1A2 (0.43) | MAOBMAOAMAPTMEN1USP2 | |
| SCHEMBL11686425 | 0.84 | KDM4E (0.45) | MAOBMAOAPOLBMEN1USP2 | |
| Hydrochloric Acid SCHEMBL11683553 | 0.84 | MAOA (0.54) | MAOBMAOAMAPTMEN1KMT2A | |
| SCHEMBL11683898 | 0.84 | MAOB (0.58) | MAOBMAOAMAPTGAAPOLB | |
| Hydrochloric Acid SCHEMBL11684929 | 0.83 | MAOB (0.57) | MAOBMAOAMAPTGAAPOLB | |
| SCHEMBL11684463 | 0.82 | MAOB (0.49) | MAOBMAOAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4006234-A | Substituted 2-benzofuranyl propenones as anti-tubercular agents | AMERICAN CYANAMID COMPANY (US) | 1977-02-01 | — | — | US | disclosed |
| US-3931157-A | ANTITUBERCULAR | AMERICAN CYANAMID COMPANY (US) | 1976-01-06 | — | — | US | disclosed |