SCHEMBL11686374

SCHEMBL11686374

CC1NC(=O)OC1c1ccc2ccccc2c1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 6/20 0.40
SLC6A2 P23975 5/20 0.40
SLC6A3 Q01959 5/20 0.40
CYP2D6 P10635 3/20 0.40
CYP3A4 P08684 2/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
MMP13 P45452 1/20 0.38
GRM5 P41594 5/20 0.38
KCNH2 Q12809 1/20 0.38
IDH1 O75874 1/20 0.37
DRD2 P14416 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3119262 0.79 GRM5 (0.49) SLC6A2SLC6A3CYP2D6GRM5
SCHEMBL8532996 0.79 GRM5 (0.49) SLC6A2SLC6A3CYP2D6GRM5
SCHEMBL4687 0.79 GRM5 (0.49) SLC6A2SLC6A3CYP2D6GRM5
SCHEMBL5835621 0.79 GRM5 (0.49) SLC6A2SLC6A3CYP2D6GRM5
SCHEMBL4291 0.79 GRM5 (0.49) SLC6A2SLC6A3CYP2D6GRM5
SCHEMBL338191 0.79 GRM5 (0.49) SLC6A2SLC6A3CYP2D6GRM5
SCHEMBL6374631 0.79 GRM5 (0.49) SLC6A2SLC6A3CYP2D6GRM5
SCHEMBL5544656 0.79 GRM5 (0.49) SLC6A2SLC6A3CYP2D6GRM5
SCHEMBL8192290 0.79 GRM5 (0.49) SLC6A2SLC6A3CYP2D6GRM5
SCHEMBL7655582 0.77 GRM5 (0.54) GRM5KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4009039-A Heat developable light-sensitive oxazoline containing element FUJI PHOTO FILM CO., LTD. (JA) 1977-02-22 US disclosed