Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11685282 | 0.96 | MAOA (0.41) | MAOAMAOBTP53SMN1; SMN2EPHX1 | |
| SCHEMBL2231647 | 0.80 | GAA (0.58) | SMN1; SMN2TSHRGAAALOX12CYP2C19 | |
| SCHEMBL11685289 | 0.77 | GAA (0.54) | MAOAMAOBSMN1; SMN2CLK4GAA | |
| SCHEMBL23447277 | 0.74 | NPC1 (0.54) | TP53SMN1; SMN2EPHX1TSHREPHX2 | |
| SCHEMBL10998968 | 0.72 | SMN1; SMN2 (0.42) | MAOAMAOBTP53SMN1; SMN2EPHX1 | |
| SCHEMBL23447724 | 0.70 | MAPT (0.71) | TP53SMN1; SMN2EPHX2GAARAB9A | |
| SCHEMBL13648229 | 0.69 | SMN1; SMN2 (0.70) | MAOAMAOBTP53SMN1; SMN2EPHX1 | |
| SCHEMBL474941 | 0.69 | HDAC1 (0.65) | TP53SMN1; SMN2EPHX1TSHREPHX2 | |
| SCHEMBL24713130 | 0.69 | EPHX2 (0.58) | TP53EPHX2RAB9AKMT2AMAPT | |
| SCHEMBL4154196 | 0.68 | CA12 (0.56) | TP53SMN1; SMN2EPHX2GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4030925-A | Photographic compositions and elements including internal latent image silver halide grains and acylhydrazinophenylthiourea nucleating agents therefor | EASTMAN KODAK COMPANY (US) | 1977-06-21 | — | — | US | disclosed |
| US-4031127-A | Acyl hydrazino thiourea derivatives as photographic nucleating agents | EASTMAN KODAK COMPANY (US) | 1977-06-21 | — | — | US | disclosed |