Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 10/20 | 0.80 |
| ▸ | PGR | P06401 | 7/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.60 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.60 |
| ▸ | IL5 | P05113 | 1/20 | 0.60 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.60 |
| ▸ | AR | P10275 | 1/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
| ▸ | MMP9 | P14780 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | THPO | P40225 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18600487 | 0.95 | NR3C1 (0.85) | NR3C1PGRCYP3A4HIF1ALMNA | |
| SCHEMBL12396790 | 0.95 | NR3C1 (0.85) | NR3C1PGRCYP3A4HIF1ALMNA | |
| SCHEMBL13177824 | 0.95 | NR3C1 (0.85) | NR3C1PGRCYP3A4HIF1ALMNA | |
| SCHEMBL18600314 | 0.93 | NR3C1 (0.80) | NR3C1PGRCYP3A4HIF1ALMNA | |
| SCHEMBL13177840 | 0.90 | NR3C1 (0.81) | NR3C1PGRCYP3A4HIF1ALMNA | |
| Desonide SCHEMBL1649865 | 0.89 | NR3C1 (1.00) | NR3C1PGRCYP3A4HIF1ALMNA | |
| Desonide SCHEMBL1650014 | 0.89 | NR3C1 (1.00) | NR3C1PGRCYP3A4HIF1ALMNA | |
| Desonide SCHEMBL21570018 | 0.89 | NR3C1 (1.00) | NR3C1PGRCYP3A4HIF1ALMNA | |
| Desonide SCHEMBL12235707 | 0.89 | NR3C1 (1.00) | NR3C1PGRCYP3A4HIF1ALMNA | |
| Desonide SCHEMBL5481974 | 0.89 | NR3C1 (1.00) | NR3C1PGRCYP3A4HIF1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4049804-A | Novel pregnanoic acid derivatives | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-09-20 | — | — | US | claimed |
| US-4049804-A | Novel pregnanoic acid derivatives | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-09-20 | — | — | US | disclosed |