Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15600036 | 0.81 | CHRNA7 (0.33) | CHRNA7 | |
| SCHEMBL21101296 | 0.79 | LMNA (0.30) | — | |
| SCHEMBL21101473 | 0.76 | CHRNA7 (0.34) | CHRNA7 | |
| SCHEMBL7307898 | 0.72 | — | — | |
| SCHEMBL519399 | 0.72 | — | — | |
| SCHEMBL23462594 | 0.68 | CHRNA7 (0.35) | CHRNA7SMN1; SMN2PTGER3PDE4BPDE4D | |
| SCHEMBL21101213 | 0.67 | LMNA (0.31) | — | |
| SCHEMBL16906153 | 0.67 | SMN1; SMN2 (0.45) | CHRNA7SMN1; SMN2PTGER3PDE4BPDE4D | |
| SCHEMBL2284513 | 0.65 | — | — | |
| SCHEMBL25239019 | 0.65 | LMNA (0.41) | CHRNA7SMN1; SMN2PTGER3PDE4BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243851-A1 | BRIDGED COMPOUNDS AS AGONISTS OF THE MUSCARINIC M1 AND/OR M4 RECEPTOR | HEPTARES THERAPEUTICS LIMITED (GB) | 2019-12-26 | — | — | WO | disclosed |
| US-4009039-A | Heat developable light-sensitive oxazoline containing element | FUJI PHOTO FILM CO., LTD. (JA) | 1977-02-22 | — | — | US | disclosed |