Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.68 |
| ▸ | PIM1 | P11309 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.57 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | G6PD | P11413 | 1/20 | 0.57 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.57 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.57 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25167179 | 0.88 | MAPT (0.78) | EGFRPIM1MAPTKDM4EMAPK1 | |
| SCHEMBL28916427 | 0.87 | KMT2A (0.79) | EGFRPIM1MAPTKDM4EMAPK1 | |
| SCHEMBL11134106 | 0.86 | MAPT (0.73) | EGFRPIM1MAPTKDM4EMAPK1 | |
| SCHEMBL23199095 | 0.82 | ALDH1A1 (0.60) | EGFRPIM1MAPTKDM4EMAPK1 | |
| SCHEMBL5806074 | 0.82 | MAPT (0.61) | EGFRPIM1MAPTKDM4EMAPK1 | |
| SCHEMBL11528272 | 0.81 | EGFR (1.00) | EGFRPIM1MAPTKDM4EMAPK1 | |
| SCHEMBL17265615 | 0.79 | PIM1 (0.66) | EGFRPIM1MAPTKDM4EMAPK1 | |
| SCHEMBL16227013 | 0.79 | EGFR (0.57) | EGFRPIM1MAPTKDM4EMAPK1 | |
| SCHEMBL3192484 | 0.78 | CSNK2A2 (0.70) | EGFRPIM1MAPTKDM4EMAPK1 | |
| SCHEMBL5821883 | 0.77 | EGFR (0.51) | EGFRPIM1MAPTKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4021457-A | Intermediates for polycyclic quinonoid antibiotics | RESEARCH CORPORATION (US) | 1977-05-03 | — | — | US | disclosed |