Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | F2R | P25116 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | UBE2M | P61081 | 1/20 | 0.47 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16724727 | 0.90 | MEN1 (0.66) | MEN1KMT2AALDH1A1NPSR1MTOR | |
| SCHEMBL11695167 | 0.88 | HDAC1 (0.48) | MEN1KMT2AALDH1A1NPSR1MTOR | |
| SCHEMBL11695774 | 0.86 | EGFR (0.54) | MEN1KMT2AALDH1A1NPSR1MTOR | |
| SCHEMBL11693120 | 0.86 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1NPSR1MTOR | |
| SCHEMBL11709393 | 0.83 | MAPT (0.69) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL29140946 | 0.77 | MTOR (0.61) | MEN1KMT2AALDH1A1NPSR1MTOR | |
| SCHEMBL10595774 | 0.75 | NAMPT (0.53) | MEN1KMT2AALDH1A1NPSR1MTOR | |
| SCHEMBL29140894 | 0.75 | ALDH1A1 (0.78) | MEN1KMT2AALDH1A1NPSR1HDAC1 | |
| SCHEMBL10716551 | 0.75 | ALDH1A1 (0.53) | ALDH1A1NPSR1MTORHDAC1HDAC6 | |
| SCHEMBL11691549 | 0.75 | EGFR (0.51) | ALDH1A1NPSR1MTORHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4010281-A | N-(4-HALOBENZYL)-N-BRANCHED ALKYL-N'-PHENYLUREAS AND FUNGICIDAL USE THEREOF | BAYER AKTIENGESELLSCHAFT (DT) | 1977-03-01 | — | — | US | claimed |