Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.72 |
| ▸ | RAB9A | P51151 | 6/20 | 0.72 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ATM | Q13315 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11693234 | 1.00 | NPC1 (0.72) | NPC1RAB9AMAPTLMNACYP3A4 | |
| SCHEMBL14926696 | 0.91 | NPC1 (0.62) | NPC1RAB9AMAPTLMNACYP3A4 | |
| SCHEMBL14926679 | 0.89 | MAPT (0.60) | NPC1RAB9AMAPTLMNACYP3A4 | |
| SCHEMBL13312943 | 0.89 | MAPT (0.60) | NPC1RAB9AMAPTLMNACYP3A4 | |
| SCHEMBL18590721 | 0.89 | MAPT (0.60) | NPC1RAB9AMAPTLMNACYP3A4 | |
| SCHEMBL14926692 | 0.89 | MAPT (0.60) | NPC1RAB9AMAPTLMNACYP3A4 | |
| SCHEMBL22755750 | 0.87 | NPC1 (0.59) | NPC1RAB9AMAPTLMNACYP3A4 | |
| SCHEMBL8189665 | 0.85 | NPC1 (0.57) | NPC1RAB9AMAPTLMNACYP3A4 | |
| SCHEMBL10038795 | 0.85 | NPC1 (0.56) | NPC1RAB9AMAPTLMNACYP3A4 | |
| SCHEMBL15677254 | 0.85 | NPC1 (0.56) | NPC1RAB9AMAPTLMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4058607-A | DIHALOVINYL DIALKYL PHOSPHATE, 1,3-BENZODIOXOLES | AIRWICK INDUSTRIES, INC. (US) | 1977-11-15 | — | — | US | disclosed |
| US-3966900-A | INSECTICIDES | AIRWICK INDUSTRIES, INC. (US) | 1976-06-29 | — | — | US | disclosed |