SCHEMBL11694201

SCHEMBL11694201

CC(NC(C)(C)Cc1ccc(O)cc1)C(=O)c1ccc(O)c(O)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.48
GAA P10253 2/20 0.48
RECQL P46063 2/20 0.48
DBH P09172 1/20 0.48
CYP2B6 P20813 1/20 0.47
SLC6A2 P23975 6/20 0.44
SLC6A3 Q01959 5/20 0.44
CHRNA1 P02708 4/20 0.44
CHRNG P07510 4/20 0.44
CHRNB1 P11230 4/20 0.44
CHRNB2 P17787 4/20 0.44
CHRNB4 P30926 4/20 0.44
CHRNA3 P32297 4/20 0.44
CHRNA4 P43681 4/20 0.44
CHRND Q07001 4/20 0.44
SLC6A4 P31645 4/20 0.44
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
TSHR P16473 1/20 0.41
ALDH1A1 P00352 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11688982 0.89 KDM4E (0.47) KDM4EGAARECQLDBHCYP2B6
Hydrochloric Acid SCHEMBL11280550 0.78 SLC6A3 (0.63) KDM4EGAARECQLDBHCYP2B6
Hydrochloric Acid SCHEMBL11692942 0.77 KDM4E (0.44) KDM4EGAARECQLDBHCYP2B6
Hydrochloric Acid SCHEMBL11694725 0.75 KDM4E (0.49) KDM4EGAARECQLDBHSLC6A2
Bromide SCHEMBL11689029 0.75 KDM4E (0.49) KDM4EGAARECQLDBHSLC6A2
SCHEMBL10656522 0.74 CYP2B6 (0.51) CYP2B6SLC6A2SLC6A3CHRNA1CHRNG
SCHEMBL10663279 0.73 CYP2B6 (0.73) CYP2B6SLC6A2SLC6A3CHRNA1CHRNG
Hydrochloric Acid SCHEMBL10656473 0.72 CYP2B6 (0.71) CYP2B6SLC6A2SLC6A3CHRNA1CHRNG
Hydrochloric Acid SCHEMBL10655169 0.72 CYP2B6 (0.50) CYP2B6SLC6A2SLC6A3CHRNA1CHRNG
SCHEMBL10657745 0.71 CYP2B6 (0.52) CYP2B6SLC6A2SLC6A3CHRNA1CHRNG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4042713-A SYMPATHOMIMETIC BOEHRINGER INGELHEIM GMBH (DT) 1977-08-16 US disclosed