SCHEMBL11694395

SCHEMBL11694395

CC(=O)OC(C)(C)N=N[Ge](C)(C)C

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
TSHR P16473 1/20 0.47
CYP2C19 P33261 1/20 0.47
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11694391 1.00 CYP2D6 (0.47) CYP2D6CYP2C9TSHRCYP2C19GAA
SCHEMBL23549 0.81 TSHR (0.52) CYP2D6CYP2C9TSHRCYP2C19GAA
SCHEMBL23548 0.81 TSHR (0.52) CYP2D6CYP2C9TSHRCYP2C19GAA
SCHEMBL11427704 0.75 TSHR (0.47) CYP2D6CYP2C9TSHRCYP2C19GAA
SCHEMBL11427707 0.75 TSHR (0.47) CYP2D6CYP2C9TSHRCYP2C19GAA
SCHEMBL11061827 0.70 TSHR (0.43) CYP2D6CYP2C9TSHRCYP2C19GAA
SCHEMBL10898803 0.68 TSHR (0.42) CYP2D6CYP2C9TSHRCYP2C19GAA
SCHEMBL10897591 0.68 TSHR (0.42) CYP2D6CYP2C9TSHRCYP2C19GAA
SCHEMBL11423083 0.67 CYP2C9 (0.71) CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL11423080 0.67 CYP2C9 (0.71) CYP2D6CYP2C9TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4029615-A AZO COMPOUNDS PENNWALT CORPORATION (US) 1977-06-14 US disclosed
US-3993609-A ACID SENSITIVE AZO PROMOTERS PENNWALT CORPORATION (US) 1976-11-23 US disclosed