Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11694394 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTALDH1A1LMNARAB9A | |
| SCHEMBL11693417 | 0.85 | EGLN1 (0.42) | SMN1; SMN2MAPTALDH1A1LMNARAB9A | |
| SCHEMBL11693418 | 0.85 | EGLN1 (0.42) | SMN1; SMN2MAPTALDH1A1LMNARAB9A | |
| SCHEMBL11690502 | 0.84 | MAPT (0.42) | SMN1; SMN2MAPTALDH1A1LMNARAB9A | |
| SCHEMBL11690506 | 0.84 | MAPT (0.42) | SMN1; SMN2MAPTALDH1A1LMNARAB9A | |
| SCHEMBL11696110 | 0.82 | MAPK1 (0.55) | SMN1; SMN2MAPTALDH1A1LMNARAB9A | |
| SCHEMBL11692201 | 0.82 | MAPK1 (0.55) | SMN1; SMN2MAPTALDH1A1LMNARAB9A | |
| SCHEMBL11692408 | 0.81 | MAPK1 (0.54) | SMN1; SMN2MAPTALDH1A1LMNARAB9A | |
| SCHEMBL11696289 | 0.79 | CA12 (0.43) | SMN1; SMN2MAPTALDH1A1LMNARAB9A | |
| SCHEMBL11696285 | 0.79 | CA12 (0.43) | SMN1; SMN2MAPTALDH1A1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4018785-A | ANTIINFLAMMATORY, ANTIRHEUMATIC, ANALGESIC, ANTIPYRETIC | SHIONOGI & CO., LTD. (JA) | 1977-04-19 | — | — | US | disclosed |