Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | RGS12 | O14924 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.50 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.50 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.50 |
| ▸ | FLT4 | P35916 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11687814 | 0.95 | POLB (0.55) | MAPTPOLBHTTMEN1RGS12 | |
| Butane SCHEMBL11876142 | 0.88 | MEN1 (0.65) | MAPTPOLBHTTMEN1RGS12 | |
| SCHEMBL9702399 | 0.86 | ALDH1A1 (0.62) | MAPTPOLBHTTMEN1RGS12 | |
| SCHEMBL11687308 | 0.86 | ALDH1A1 (0.53) | MAPTPOLBHTTMEN1RGS12 | |
| SCHEMBL28495677 | 0.84 | MEN1 (0.60) | MAPTPOLBHTTMEN1RGS12 | |
| SCHEMBL28552747 | 0.81 | MEN1 (0.55) | MAPTPOLBHTTMEN1RGS12 | |
| SCHEMBL11689750 | 0.80 | KDM4E (0.45) | MAPTPOLBHTTMEN1RGS12 | |
| Hydrochloric Acid SCHEMBL9080391 | 0.80 | ALDH1A1 (0.59) | MAPTPOLBHTTMEN1KMT2A | |
| SCHEMBL14817770 | 0.77 | KMT2A (0.81) | MAPTPOLBHTTMEN1RGS12 | |
| SCHEMBL4095911 | 0.76 | MEN1 (0.48) | MAPTPOLBHTTMEN1RGS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4022799-A | DYEING, PRINTING OF NATURAL AND SYNTHETIC MATERIALS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-10 | — | — | US | disclosed |
| US-3950347-A | NAPHTHOLACTAM DYESTUFFS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-13 | — | — | US | disclosed |