Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | CASP1 | P29466 | 2/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | CASP7 | P55210 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | SCN1A | P35498 | 1/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.50 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11701198 | 0.91 | KDM4E (0.51) | GAAKDM4EMAPTALDH1A1POLB | |
| SCHEMBL27577886 | 0.89 | SMPD1 (0.56) | GAAKDM4EMAPTALDH1A1POLB | |
| SCHEMBL808653 | 0.87 | SMPD1 (0.58) | GAAKDM4EMAPTALDH1A1POLB | |
| SCHEMBL9794555 | 0.87 | MAPT (0.66) | GAAKDM4EMAPTALDH1A1POLB | |
| SCHEMBL5162262 | 0.86 | CA1 (0.45) | GAAKDM4EMAPTALDH1A1POLB | |
| SCHEMBL9353738 | 0.84 | MAPT (0.61) | GAAKDM4EMAPTALDH1A1POLB | |
| SCHEMBL2442358 | 0.82 | MAOB (0.55) | GAAKDM4EMAPTALDH1A1POLB | |
| SCHEMBL4392029 | 0.82 | ESR1 (0.48) | GAAKDM4EMAPTALDH1A1POLB | |
| SCHEMBL30118840 | 0.82 | MAOB (0.55) | GAAKDM4EMAPTALDH1A1POLB | |
| SCHEMBL5446140 | 0.82 | GAA (0.65) | GAAKDM4EMAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4032559-A | PICKLING INHIBITORS, HYPOTENSIVE, SALTS OF MOTHPROOFING AGENTS | THE UPJOHN COMPANY (US) | 1977-06-28 | — | — | US | disclosed |
| US-4007212-A | Novel amide compounds | POLAROID CORPORATION (US) | 1977-02-08 | — | — | US | disclosed |