SCHEMBL808653

SCHEMBL808653

CCCCCCCCCCCCOc1cc(N)ccc1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMPD1 P17405 1/20 0.58
TSHR P16473 1/20 0.54
ESR1 P03372 2/20 0.50
MAPT P10636 3/20 0.49
ALDH1A1 P00352 2/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
KDM4E B2RXH2 1/20 0.49
USP2 O75604 1/20 0.49
TP53 P04637 1/20 0.49
POLB P06746 1/20 0.49
GAA P10253 1/20 0.49
CASP1 P29466 1/20 0.49
HTT P42858 1/20 0.49
CASP7 P55210 1/20 0.49
ATM Q13315 1/20 0.49
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
NR5A1 Q13285 1/20 0.47
TLR8 Q9NR97 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27577886 0.98 SMPD1 (0.56) SMPD1TSHRESR1MAPTALDH1A1
SCHEMBL11701198 0.93 KDM4E (0.51) SMPD1TSHRESR1MAPTALDH1A1
SCHEMBL11697103 0.87 GAA (0.62) SMPD1TSHRMAPTALDH1A1MEN1
SCHEMBL17817108 0.86 TSHR (0.57) SMPD1TSHRMAPTALDH1A1MEN1
SCHEMBL7043129 0.86 TSHR (0.57) SMPD1TSHRMAPTALDH1A1MEN1
SCHEMBL7045171 0.86 TSHR (0.57) SMPD1TSHRMAPTALDH1A1MEN1
SCHEMBL1608893 0.86 TSHR (0.57) SMPD1TSHRMAPTALDH1A1MEN1
SCHEMBL9168790 0.86 TSHR (0.57) SMPD1TSHRMAPTALDH1A1MEN1
SCHEMBL7045133 0.86 TSHR (0.57) SMPD1TSHRMAPTALDH1A1MEN1
SCHEMBL3278460 0.86 TSHR (0.57) SMPD1TSHRMAPTALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1652881-B1 Thermal stabilizer compositions for halogen-containing vinyl polymers ROHM & HAAS (US) 2011-11-23 EP disclosed
US-7488433-B2 Thermal stabilizer compositions for halogen-containing vinyl polymers ROHM AND HAAS COMPANY (US) 2009-02-10 US disclosed
EP-1621576-B1 Thermal stabilizer compositions for halogen-containing vinyl polymers ROHM & HAAS (US) 2007-02-14 EP disclosed
US-7109261-B2 Latent mercaptans as multi-functional additives for halogen-containing polymer compositions ROHM AND HAAS COMPANY (US) 2006-09-19 US disclosed
US-7105109-B2 Latent mercaptans as stabilizers for halogen-containing polymer compositions ROHM AND HAAS COMPANY (US) 2006-09-12 US disclosed
EP-1652881-A1 Thermal stabilizer compositions for halogen-containing vinyl polymers Rohm and Haas Company (US) 2006-05-03 EP disclosed
US-20060089436-A1 Thermal stabilizer compositions for halogen-containing vinyl polymers AUSTEN STEVEN C 2006-04-27 US disclosed
US-20060079611-A1 Thermal stabilizer compositions for halogen-containing vinyl polymers AUSTEN STEVEN C 2006-04-13 US disclosed
EP-1645592-A1 Thermal stabilizer compositions for halogen-containing vinyl polymers Rohm and Haas Company (US) 2006-04-12 EP disclosed
US-7025904-B2 Method for improving adhesion of water-based inks to halogen-containing resin articles ROHM AND HAAS COMPANY (US) 2006-04-11 US disclosed
EP-0890608-A2 A latent mercaptan as a heat stabilizer MORTON INTERNATIONAL, INC. (US) 1999-01-13 EP disclosed
EP-0742259-A1 Latent mercaptans as multi-functional additives for halogen-containing polymer compositions MORTON INTERNATIONAL, INC. (US) 1996-11-13 EP disclosed
US-4342875-A STABILIZERS FOR OLEFIN POLYMERS CINCINNATI-MILACRON, INC. (US) 1982-08-03 US disclosed
US-4179432-A 2-HYDROXYBENZOPHENONE, ORGANOTIN MERCAPTIDE PHOTOSTABILITY CINCINNATI MILACRON CHEMICALS, INC. (US) 1979-12-18 US disclosed
US-RE29523-E Olefinic polymers stabilized with thioacyl trivalent phosphorus compounds BORG-WARNER CORPORATION (US) 1978-01-24 US disclosed
US-4064100-A HEAT AND LIGHT STABILIZERS FOR POLYMERS, CONTAINERS FOR FOOD WESTON CHEMICAL CO., INC. (US) 1977-12-20 US disclosed
US-4012399-A ULTRAVIOLET LIGHT ABSORBERS AND STABILIZERS CINCINNATI MILACRON CHEMICALS, INC. (US) 1977-03-15 US disclosed
US-4000101-A POLYPROPYLENE WESTON CHEMICAL CORPORATION (US) 1976-12-28 US disclosed
US-3959220-A Polymer additives comprising transition metal complexes with trivalent phosphorous compounds CINCINNATI MILACRON CHEMICALS, INC. (US) 1976-05-25 US disclosed
US-3933813-A Process for the production of mercaptoethyl containing compounds DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1976-01-20 US disclosed