Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KARS1 | Q15046 | 4/20 | 0.70 |
| ▸ | RXRA | P19793 | 1/20 | 0.70 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.70 |
| ▸ | CDK2 | P24941 | 1/20 | 0.70 |
| ▸ | RXRB | P28702 | 1/20 | 0.70 |
| ▸ | RXRG | P48443 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.58 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.58 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.57 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.57 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11697650 | 0.93 | KARS1 (0.67) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL19283114 | 0.88 | KARS1 (0.74) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL11697137 | 0.86 | KARS1 (0.69) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL20856826 | 0.86 | KARS1 (0.71) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL19293738 | 0.86 | KARS1 (0.66) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL19293725 | 0.86 | KARS1 (0.66) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL11768691 | 0.86 | KARS1 (0.74) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL11479687 | 0.85 | KARS1 (0.73) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL11480708 | 0.84 | KARS1 (0.69) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL20856811 | 0.84 | KARS1 (0.69) | KARS1RXRACCNE1CDK2RXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4009206-A | CHOLESTEROL LOWERING AGENTS | MURAI HIROMU | 1977-02-22 | — | — | US | disclosed |