Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | GSR | P00390 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 9/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11697165 | 1.00 | HDAC1 (0.53) | HDAC1HDAC8HDAC6GSRMAPT | |
| SCHEMBL4105481 | 0.85 | HDAC1 (0.57) | HDAC1HDAC8HDAC6GSRMAPT | |
| SCHEMBL15128556 | 0.83 | HDAC1 (0.49) | HDAC1HDAC8HDAC6GSRMAPT | |
| SCHEMBL5680290 | 0.82 | MAOB (0.57) | HDAC1HDAC8HDAC6GSRMAPT | |
| SCHEMBL5680288 | 0.82 | MAOB (0.57) | HDAC1HDAC8HDAC6GSRMAPT | |
| SCHEMBL11233528 | 0.80 | NFE2L2 (0.62) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11233530 | 0.80 | NFE2L2 (0.62) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL10493256 | 0.78 | NPC1 (0.57) | HDAC1HDAC8HDAC6MAPTMEN1 | |
| SCHEMBL10493248 | 0.78 | NPC1 (0.57) | HDAC1HDAC8HDAC6MAPTMEN1 | |
| SCHEMBL10576204 | 0.78 | MAOB (0.47) | HDAC1HDAC8HDAC6GSRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4061630-A | 7-Substituted-ureido-3-carbamoyloxymethyl cephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1977-12-06 | — | — | US | disclosed |