Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11693688 | 0.98 | ACACB (0.35) | ACACBACACACYP4F2CYP4A11LMNA | |
| SCHEMBL16078698 | 0.90 | LMNA (0.50) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL16078640 | 0.90 | LMNA (0.50) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL16078700 | 0.90 | LMNA (0.50) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL16078690 | 0.90 | LMNA (0.50) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL16078627 | 0.90 | LMNA (0.50) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL8512233 | 0.89 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL16078688 | 0.85 | SMN1; SMN2 (0.44) | CYP4F2CYP4A11LMNAALDH1A1HSD17B10 | |
| SCHEMBL5141338 | 0.84 | — | — | |
| SCHEMBL29092835 | 0.84 | PTGS1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4057589-A | Hydroxylation of unsaturated diols to prepare novel tetraols | CHEVRON RESEARCH COMPANY (US) | 1977-11-08 | — | — | US | disclosed |
| US-3991126-A | CHEMICAL INTERMEDIATES AND HUMECTANTS | CHEVRON RESEARCH COMPANY (US) | 1976-11-09 | — | — | US | disclosed |