Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 12/20 | 0.74 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1170029 | 0.87 | CXCR3 (0.79) | CXCR3KCNA5KMT2AMEN1PDE4A | |
| SCHEMBL12863694 | 0.86 | CXCR3 (0.75) | CXCR3KCNA5KMT2AMEN1TAS2R14 | |
| SCHEMBL3436412 | 0.83 | CXCR3 (0.72) | CXCR3KCNA5KMT2AMEN1PDE4A | |
| SCHEMBL1169968 | 0.82 | CXCR3 (0.74) | CXCR3KCNA5KMT2APDE4APDE4B | |
| SCHEMBL1169383 | 0.82 | CXCR3 (0.78) | CXCR3KCNA5KMT2AMEN1TAS2R14 | |
| SCHEMBL1169766 | 0.82 | CXCR3 (0.78) | CXCR3KCNA5KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL12863313 | 0.81 | CXCR3 (0.80) | CXCR3KCNA5KMT2AALDH1A1HPGD | |
| SCHEMBL1169731 | 0.81 | CXCR3 (0.69) | CXCR3KCNA5KMT2AALDH1A1TSHR | |
| SCHEMBL13649423 | 0.80 | CXCR3 (0.71) | CXCR3KCNA5KMT2AMEN1PDE4A | |
| SCHEMBL1169939 | 0.79 | CXCR3 (0.71) | CXCR3KCNA5KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028509-A1 | Sulfonamides | MERCK SERONO SA (CH) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028509-A1 | Sulfonamides | CXCR3, CXCR2, CXCR1 | CXCR3 1/4885KCNA5 1177/4885KMT2A 1412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.