Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11694982 | 0.79 | MAPT (0.53) | PABPC1KMT2AATMMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL11699040 | 0.78 | PABPC1 (0.61) | PABPC1KMT2AATMMAPTALDH1A1 | |
| Iodide SCHEMBL11698515 | 0.78 | PABPC1 (0.71) | PABPC1KMT2AATMMAPTALDH1A1 | |
| Bromide SCHEMBL10921409 | 0.78 | KDM4E (0.70) | PABPC1KMT2AATMMAPTALDH1A1 | |
| SCHEMBL10916379 | 0.73 | PABPC1 (0.96) | PABPC1KMT2AATMMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL6151874 | 0.72 | MAPT (0.71) | PABPC1KMT2AATMMAPTALDH1A1 | |
| Bromide SCHEMBL1313738 | 0.71 | PABPC1 (0.93) | PABPC1KMT2AATMMAPTALDH1A1 | |
| Iodide SCHEMBL11697562 | 0.71 | PABPC1 (0.80) | PABPC1KMT2AATMMAPTALDH1A1 | |
| Iodide SCHEMBL11696180 | 0.69 | MAPT (0.57) | PABPC1KMT2AATMMAPTALDH1A1 | |
| SCHEMBL26709140 | 0.69 | PABPC1 (0.77) | PABPC1KMT2AATMMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE29153-E | HERBICIDES, INSECTICIDES | MONSANTO COMPANY (US) | 1977-03-15 | — | — | US | disclosed |