Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.62 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.54 |
| ▸ | NAAA | Q02083 | 3/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.51 |
| ▸ | PRKCA | P17252 | 2/20 | 0.49 |
| ▸ | PAM | P19021 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11857174 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL11696054 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL11850674 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL11859562 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL11695346 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL11852854 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL11858462 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL11848872 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL11693776 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL11692278 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3948961-A | CYCLOPROPYL ALKYL CARBOXYLATES, MITICIDE, INSECTICIDE | ZOECON CORPORATION (US) | 1976-04-06 | — | — | US | claimed |
| US-4014922-A | CYCLOPROPYL SUBSTITUTED ESTERS; MITICIDES | ZOECON CORPORATION (US) | 1977-03-29 | — | — | US | disclosed |
| US-3948961-A | CYCLOPROPYL ALKYL CARBOXYLATES, MITICIDE, INSECTICIDE | ZOECON CORPORATION (US) | 1976-04-06 | — | — | US | disclosed |