Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 2/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 10/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.41 |
| ▸ | TTK | P33981 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL922865 | 0.80 | JAK2 (0.55) | ITKLRRK2CHUKTTK | |
| SCHEMBL11701839 | 0.76 | GSK3B (0.66) | GSK3B | |
| SCHEMBL11696884 | 0.75 | FADS1 (0.55) | ITKGSK3B | |
| SCHEMBL2870356 | 0.75 | ITK (0.50) | ITKLRRK2GSK3BCHUKTTK | |
| SCHEMBL31587042 | 0.75 | ITK (0.50) | ITKLRRK2CHUKTTK | |
| SCHEMBL4782691 | 0.75 | LRRK2 (0.52) | ITKLRRK2CHUKTTK | |
| SCHEMBL11701250 | 0.75 | FADS1 (0.55) | ITKMCHR1GSK3B | |
| SCHEMBL13122264 | 0.75 | ITK (0.50) | ITKLRRK2CHUKTTK | |
| SCHEMBL11697624 | 0.75 | FADS1 (0.60) | MCHR1GSK3B | |
| SCHEMBL29584191 | 0.75 | LRRK2 (0.52) | ITKLRRK2CHUKTTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4065568-A | 3-Carbo(lower alkoxy)hydrazinoindazoles | BAYER AKTIENGESELLSCHAFT (DT) | 1977-12-27 | — | — | US | disclosed |