SCHEMBL11699264

SCHEMBL11699264

CCN(CC)c1ccc(N=Nc2ccc([N+](=O)[O-])cc2Cl)c(C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.43
MEN1 O00255 7/20 0.43
NPC1 O15118 3/20 0.43
S100B P04271 1/20 0.41
HSD17B10 Q99714 1/20 0.41
KDR P35968 1/20 0.40
ALDH1A1 P00352 9/20 0.40
MAPT P10636 9/20 0.40
HTT P42858 2/20 0.40
TP53 P04637 1/20 0.40
POLB P06746 2/20 0.38
TDP1 Q9NUW8 3/20 0.38
TSHR P16473 1/20 0.38
RAB9A P51151 2/20 0.37
MCL1 Q07820 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
TLR9 Q9NR96 1/20 0.37
NPSR1 Q6W5P4 3/20 0.37
LMNA P02545 3/20 0.37
MAPK1 P28482 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11699257 1.00 KMT2A (0.43) KMT2AMEN1NPC1S100BHSD17B10
SCHEMBL23695626 0.95 MEN1 (0.41) KMT2AMEN1NPC1S100BHSD17B10
SCHEMBL23695315 0.92 HSD17B10 (0.45) KMT2AMEN1NPC1HSD17B10ALDH1A1
SCHEMBL9493418 0.88 MAPT (0.38) KMT2AMEN1NPC1HSD17B10KDR
SCHEMBL11591735 0.88 MEN1 (0.38) KMT2AMEN1NPC1S100BHSD17B10
SCHEMBL30440420 0.88 MAPT (0.38) KMT2AMEN1NPC1HSD17B10KDR
SCHEMBL9493420 0.88 MAPT (0.38) KMT2AMEN1NPC1HSD17B10KDR
SCHEMBL29527780 0.87 MAPT (0.53) KMT2AMEN1NPC1HSD17B10KDR
SCHEMBL11429772 0.87 MAPT (0.53) KMT2AMEN1NPC1HSD17B10KDR
SCHEMBL11429778 0.87 MAPT (0.53) KMT2AMEN1NPC1HSD17B10KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4058607-A DIHALOVINYL DIALKYL PHOSPHATE, 1,3-BENZODIOXOLES AIRWICK INDUSTRIES, INC. (US) 1977-11-15 US disclosed
US-3966900-A INSECTICIDES AIRWICK INDUSTRIES, INC. (US) 1976-06-29 US disclosed