Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30440420 | 1.00 | MAPT (0.38) | MAPTALDH1A1KMT2AKDM4EGAA | |
| SCHEMBL9493420 | 1.00 | MAPT (0.38) | MAPTALDH1A1KMT2AKDM4EGAA | |
| SCHEMBL15279879 | 0.90 | KDR (0.40) | MAPTALDH1A1KMT2AKDM4EGAA | |
| SCHEMBL15279743 | 0.90 | KDR (0.40) | MAPTALDH1A1KMT2AKDM4EGAA | |
| SCHEMBL29363816 | 0.89 | MAPT (0.40) | MAPTALDH1A1KMT2AKDM4EGAA | |
| SCHEMBL11444005 | 0.89 | MAPT (0.40) | MAPTALDH1A1KMT2AKDM4EGAA | |
| SCHEMBL11699257 | 0.88 | KMT2A (0.43) | MAPTALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL11699264 | 0.88 | KMT2A (0.43) | MAPTALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL11591735 | 0.84 | MEN1 (0.38) | MAPTALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL23695626 | 0.84 | MEN1 (0.41) | MAPTALDH1A1KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0305885-B1 | ESTERS OF RESIN ON THE BASIS OF OXYALKYLATES OF NOVOLAK, THEIR FABRICATION AND USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-04-28 | — | — | EP | disclosed |
| US-5100989-A | RESIN ACID ESTERS BASED ON NOVOLAK OXYALKYLATES, THEIR PREPARATION AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-03-31 | — | — | US | disclosed |
| EP-0305885-A2 | Esters of resin on the basis of oxyalkylates of novolak, their fabrication and use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-03-08 | — | — | EP | disclosed |