SCHEMBL11699301

SCHEMBL11699301

C=CCc1cc2c(cc1CCCC)OCO2

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.47
CYP1A2 P05177 1/20 0.47
MAPT P10636 1/20 0.47
ALDH1A1 P00352 3/20 0.47
TSHR P16473 1/20 0.47
SCN1A P35498 1/20 0.40
SCN2A Q99250 1/20 0.40
SCN3A Q9NY46 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
POLB P06746 2/20 0.39
ALOX15 P16050 1/20 0.39
ACHE P22303 1/20 0.35
PDIA3 P30101 1/20 0.35
PDIA6 Q15084 1/20 0.35
HPGD P15428 1/20 0.34
TAS1R3 Q7RTX0 1/20 0.33
TAS1R1 Q7RTX1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11699311 0.79 ALDH1A1 (0.30) CYP3A4ALDH1A1TSHR
SCHEMBL28181989 0.78 TYR (0.47) CYP3A4MAPTALDH1A1TSHRPOLB
SCHEMBL18633195 0.77 ALDH1A1 (0.50) CYP3A4CYP1A2MAPTALDH1A1TSHR
SCHEMBL11696893 0.75 CYP3A4 (0.53) CYP3A4CYP1A2MAPTALDH1A1SMN1; SMN2
Safrole SCHEMBL28246837 0.74 CYP3A4 (0.81) CYP3A4CYP1A2MAPTALDH1A1SMN1; SMN2
SCHEMBL14308074 0.74 TYR (0.50) CYP3A4MAPTALDH1A1TSHRPOLB
SCHEMBL22702252 0.74 CYP3A4 (0.46) CYP3A4CYP1A2MAPTALDH1A1TSHR
SCHEMBL12640663 0.74 TYR (0.50) CYP3A4MAPTALDH1A1TSHRSCN1A
SCHEMBL1276635 0.73 CYP3A4 (0.55) CYP3A4CYP1A2MAPTALDH1A1SMN1; SMN2
SCHEMBL7797624 0.72 CYP3A4 (0.53) CYP3A4CYP1A2MAPTALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4058607-A DIHALOVINYL DIALKYL PHOSPHATE, 1,3-BENZODIOXOLES AIRWICK INDUSTRIES, INC. (US) 1977-11-15 US disclosed
US-3962415-A Insecticide evaporator comprising DDVP with synergized benzodioxole compound as stabilizer AIRWICK INDUSTRIES, INC. (US) 1976-06-08 US disclosed