Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11694816 | 1.00 | LPAR3 (0.38) | LPAR3LPAR1LPAR2TSHRCYP3A4 | |
| SCHEMBL9754051 | 0.98 | LPAR3 (0.37) | LPAR3LPAR1LPAR2 | |
| SCHEMBL11124791 | 0.98 | TSHR (0.36) | LPAR3LPAR1LPAR2TSHRCYP3A4 | |
| SCHEMBL11695523 | 0.92 | TSHR (0.37) | TSHRCYP3A4 | |
| SCHEMBL1050586 | 0.87 | LPAR3 (0.50) | LPAR3LPAR1LPAR2CYP3A4 | |
| SCHEMBL11536052 | 0.87 | LPAR3 (0.50) | LPAR3LPAR1LPAR2CYP3A4 | |
| SCHEMBL10626501 | 0.87 | LPAR3 (0.50) | LPAR3LPAR1LPAR2CYP3A4 | |
| SCHEMBL4436294 | 0.87 | LPAR3 (0.50) | LPAR3LPAR1LPAR2CYP3A4 | |
| SCHEMBL8467826 | 0.87 | LPAR3 (0.50) | LPAR3LPAR1LPAR2CYP3A4 | |
| SCHEMBL8469249 | 0.87 | LPAR3 (0.50) | LPAR3LPAR1LPAR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4028377-A | PESTICIDES, INSECTICIDES, MITICIDES | CIBA-GEIGY CORPORATION (US) | 1977-06-07 | — | — | US | disclosed |