SCHEMBL11700142

SCHEMBL11700142

CC1=NN(c2ccccc2Cl)C(=O)C1=NNc1ccccc1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.43
MEN1 O00255 2/20 0.43
NPC1 O15118 2/20 0.43
KMT2A Q03164 2/20 0.43
LMNA P02545 1/20 0.43
RAB9A P51151 1/20 0.43
MAPK14 Q16539 4/20 0.38
MAPK11 Q15759 3/20 0.38
CHRNA7 P36544 1/20 0.38
ALDH1A1 P00352 4/20 0.37
TDP1 Q9NUW8 2/20 0.37
HPGD P15428 1/20 0.37
ALOX12 P18054 1/20 0.37
HTT P42858 1/20 0.37
GAA P10253 4/20 0.34
KDM4E B2RXH2 3/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
P2RX7 Q99572 1/20 0.33
MGLL Q99685 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11700134 1.00 MAPT (0.43) MAPTMEN1NPC1KMT2ALMNA
SCHEMBL11696282 0.87 MAPT (0.45) MAPTMEN1NPC1KMT2ALMNA
SCHEMBL11696290 0.87 MAPT (0.45) MAPTMEN1NPC1KMT2ALMNA
SCHEMBL11880373 0.86 MYC (0.35) MAPTMEN1NPC1KMT2ALMNA
SCHEMBL11695084 0.86 MYC (0.35) MAPTMEN1NPC1KMT2ALMNA
SCHEMBL16273547 0.77 BCL2 (0.53) MAPTMEN1KMT2AALDH1A1TDP1
SCHEMBL2862661 0.76 KMT2A (0.41) MAPTMEN1KMT2ALMNAALDH1A1
SCHEMBL11700148 0.73 ALB (0.36) MAPTMEN1KMT2ARAB9AALDH1A1
SCHEMBL11968683 0.72 MAPT (0.51) MAPTMEN1KMT2ALMNAALDH1A1
SCHEMBL11699306 0.72 MAPT (0.51) MAPTMEN1KMT2ALMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4058607-A DIHALOVINYL DIALKYL PHOSPHATE, 1,3-BENZODIOXOLES AIRWICK INDUSTRIES, INC. (US) 1977-11-15 US disclosed
US-3966900-A INSECTICIDES AIRWICK INDUSTRIES, INC. (US) 1976-06-29 US disclosed