SCHEMBL11700148

SCHEMBL11700148

CC1=NN(c2ccccc2Cl)C(=O)C1=NN(Cl)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALB P02768 3/20 0.36
LRRK2 Q5S007 2/20 0.36
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
HSP90AA1 P07900 1/20 0.36
MAPT P10636 3/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
MAPK1 P28482 1/20 0.35
RAB9A P51151 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
KDM4E B2RXH2 2/20 0.33
NOTUM Q6P988 1/20 0.33
ALDH1A1 P00352 3/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
GAA P10253 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALOX15 P16050 1/20 0.32
MGLL Q99685 1/20 0.32
HCAR1 Q9BXC0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11696297 0.84 KMT2A (0.50) MEN1KMT2AHSP90AA1MAPTL3MBTL1
SCHEMBL11880381 0.82 KMT2A (0.35) ALBLRRK2MEN1KMT2AHSP90AA1
SCHEMBL11700142 0.73 MAPT (0.43) ALBMEN1KMT2AMAPTRAB9A
SCHEMBL11700134 0.73 MAPT (0.43) ALBMEN1KMT2AMAPTRAB9A
SCHEMBL5941050 0.67 KMT2A (0.36) LRRK2MEN1KMT2AMAPTL3MBTL1
SCHEMBL11880373 0.67 MYC (0.35) MEN1KMT2AMAPTL3MBTL1RAB9A
SCHEMBL11695084 0.67 MYC (0.35) MEN1KMT2AMAPTL3MBTL1RAB9A
SCHEMBL11697969 0.67 KMT2A (0.51) MEN1KMT2AHSP90AA1MAPTL3MBTL1
SCHEMBL27481994 0.66 LRRK2 (0.33) LRRK2MAPTTDP1ALDH1A1GAA
SCHEMBL418891 0.66 MEN1 (0.60) MEN1KMT2AMAPTL3MBTL1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4058607-A DIHALOVINYL DIALKYL PHOSPHATE, 1,3-BENZODIOXOLES AIRWICK INDUSTRIES, INC. (US) 1977-11-15 US disclosed
US-3966900-A INSECTICIDES AIRWICK INDUSTRIES, INC. (US) 1976-06-29 US disclosed