SCHEMBL11700384

SCHEMBL11700384

CN(C(=O)Cl)C1=CCCC1

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
RAB9A P51151 1/20 0.41
HDAC3 O15379 1/20 0.34
HDAC4 P56524 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC7 Q8WUI4 1/20 0.34
HDAC2 Q92769 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
HDAC5 Q9UQL6 1/20 0.34
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11705846 0.94 ALDH1A1 (0.47) ALDH1A1RAB9AHDAC4HDAC2HDAC8
SCHEMBL11702463 0.92 ALDH1A1 (0.46) ALDH1A1RAB9AHDAC4HDAC2HDAC8
SCHEMBL11702471 0.92 ALDH1A1 (0.46) ALDH1A1RAB9AHDAC4HDAC2HDAC8
SCHEMBL11388526 0.76 ALDH1A1 (0.45) ALDH1A1RAB9AHDAC3HDAC4HDAC1
SCHEMBL8698873 0.76 ALDH1A1 (0.45) ALDH1A1RAB9AHDAC4HDAC2HDAC8
SCHEMBL10921004 0.72 ALDH1A1 (0.49) ALDH1A1RAB9AHDAC4HDAC2HDAC8
SCHEMBL517183 0.71 ALDH1A1 (0.34) ALDH1A1RAB9A
SCHEMBL516428 0.71
SCHEMBL8368179 0.71 ALDH1A1 (0.44) ALDH1A1RAB9AHDAC4HDAC2HDAC8
SCHEMBL8366202 0.71 ALDH1A1 (0.59) ALDH1A1RAB9AHDAC4HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4038311-A PRODUCTION OF N-(1-ALKENYL)-CARBAMYL CHLORIDES BASF AKTIENGESELLSCHAFT (DT) 1977-07-26 US disclosed