Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.69 |
| ▸ | POLA1 | P09884 | 4/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21424663 | 1.00 | OPRM1 (0.69) | OPRM1POLA1HSD11B1GRIN1GRIN2A | |
| SCHEMBL21424563 | 1.00 | OPRM1 (0.69) | OPRM1POLA1HSD11B1GRIN1GRIN2A | |
| SCHEMBL11701569 | 1.00 | OPRM1 (0.69) | OPRM1POLA1HSD11B1GRIN1GRIN2A | |
| SCHEMBL21042348 | 1.00 | OPRM1 (0.69) | OPRM1POLA1HSD11B1GRIN1GRIN2A | |
| SCHEMBL10411280 | 1.00 | OPRM1 (0.69) | OPRM1POLA1HSD11B1GRIN1GRIN2A | |
| SCHEMBL11700412 | 1.00 | OPRM1 (0.69) | OPRM1POLA1HSD11B1GRIN1GRIN2A | |
| SCHEMBL11699713 | 0.99 | OPRM1 (0.67) | OPRM1POLA1HSD11B1GRIN1GRIN2A | |
| SCHEMBL11699767 | 0.99 | OPRM1 (0.67) | OPRM1POLA1HSD11B1GRIN1GRIN2A | |
| SCHEMBL11699763 | 0.99 | OPRM1 (0.67) | OPRM1POLA1HSD11B1GRIN1GRIN2A | |
| SCHEMBL11702702 | 0.99 | OPRM1 (0.67) | OPRM1POLA1HSD11B1GRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4001331-A | ANTIINFLAMMATORY, ANALGESIC | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-01-04 | — | — | US | claimed |
| US-4049701-A | ANALGESICS, ANTIINFLAMMATORY | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-09-20 | — | — | US | disclosed |
| US-4001331-A | ANTIINFLAMMATORY, ANALGESIC | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |
| US-4001326-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |
| US-3979434-A | ANALGESICS, ANTIINFLAMMATORY | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-09-07 | — | — | US | disclosed |
| US-3976696-A | ANALGESIC, ANTIINFLAMMATORY | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-08-24 | — | — | US | disclosed |
| US-3976693-A | ANALGESIC, ANTIINFLAMMATORY | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-08-24 | — | — | US | disclosed |
| US-3957872-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-05-18 | — | — | US | disclosed |
| US-3937736-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-02-10 | — | — | US | disclosed |
| US-3931328-A | CARBURETOR | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-01-06 | — | — | US | disclosed |