Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL852187 | 0.89 | SRC (0.48) | TSHRCYP3A4MEN1KMT2ABLM | |
| SCHEMBL157866 | 0.82 | TSHR (0.67) | TSHRCYP3A4LMNAMEN1KMT2A | |
| SCHEMBL187454 | 0.82 | TSHR (0.67) | TSHRCYP3A4LMNAMEN1KMT2A | |
| SCHEMBL1983846 | 0.80 | TSHR (0.64) | TSHRCYP3A4LMNAMEN1KMT2A | |
| SCHEMBL17350200 | 0.80 | TSHR (0.64) | TSHRCYP3A4LMNAMEN1KMT2A | |
| SCHEMBL8884790 | 0.80 | TSHR (0.64) | TSHRCYP3A4LMNAMEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL17670022 | 0.80 | TSHR (0.64) | TSHRCYP3A4LMNAMEN1KMT2A | |
| SCHEMBL28710705 | 0.80 | TSHR (0.64) | TSHRCYP3A4LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11755908 | 0.80 | TSHR (0.64) | TSHRCYP3A4LMNAMEN1KMT2A | |
| Fluoride SCHEMBL31047203 | 0.80 | TSHR (0.64) | TSHRCYP3A4LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018127820-A2 | CELL INTERNALIZING COMPOUNDS | Sorrento Therapeutics (US) | 2018-07-12 | — | — | WO | disclosed |
| US-4024049-A | Mono and di organophosphite esters as crude oil antifoulants | NALCO CHEMICAL COMPANY (US) | 1977-05-17 | — | — | US | disclosed |