Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL157866 | 0.98 | TSHR (0.67) | TSHRCYP3A4CES2CES1LMNA | |
| Fluoride SCHEMBL31047203 | 0.95 | TSHR (0.64) | TSHRCYP3A4CES2CES1LMNA | |
| SCHEMBL1983846 | 0.95 | TSHR (0.64) | TSHRCYP3A4CES2CES1LMNA | |
| SCHEMBL218003 | 0.90 | CYP3A4 (0.57) | TSHRCYP3A4CES2CES1LMNA | |
| Toluene SCHEMBL28459052 | 0.90 | TSHR (0.57) | TSHRCYP3A4CES2CES1LMNA | |
| Naphthalene SCHEMBL15952534 | 0.88 | CYP3A4 (0.55) | TSHRCYP3A4CES2CES1LMNA | |
| Ethylenediamine SCHEMBL8467918 | 0.88 | TSHR (0.55) | TSHRCYP3A4CES2CES1LMNA | |
| SCHEMBL5597386 | 0.88 | TSHR (0.55) | TSHRCYP3A4CES2CES1LMNA | |
| P-Xylene SCHEMBL8467418 | 0.87 | SRC (0.59) | TSHRCYP3A4LMNAMEN1KMT2A | |
| SCHEMBL13422760 | 0.87 | TSHR (0.59) | TSHRCYP3A4CES2CES1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5665802-A | REACTING POLYAMIC ACID WITH A DEHYDRATION-CYCLIZATION AGENT, A CATALYST AND AN ORGANIC PHOSPHORUS COMPOUND; EXCELLENT IN TENSILE STRENGTH AND FLEXIBILITY | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1997-09-09 | — | — | US | claimed |
| US-5665802-A | REACTING POLYAMIC ACID WITH A DEHYDRATION-CYCLIZATION AGENT, A CATALYST AND AN ORGANIC PHOSPHORUS COMPOUND; EXCELLENT IN TENSILE STRENGTH AND FLEXIBILITY | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0350958-B1 | Improved polyimide and polyimide film and manufacturing method thereof | KANEGAFUCHI CHEMICAL IND (JP) | 1994-12-21 | — | — | EP | disclosed |
| EP-0350958-A2 | Improved polyimide and polyimide film and manufacturing method thereof | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-01-17 | — | — | EP | disclosed |