Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 9/20 | 0.61 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.54 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.54 |
| ▸ | TNKS | O95271 | 1/20 | 0.54 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.54 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.54 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.48 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.48 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.45 |
| ▸ | SELE | P16581 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31343926 | 0.88 | SRD5A2 (0.51) | PARP10CTNNB1TTRALDH1A1CYP3A4 | |
| SCHEMBL1855981 | 0.88 | SRD5A2 (0.51) | PARP10CTNNB1TTRALDH1A1CYP3A4 | |
| SCHEMBL1477680 | 0.88 | TTR (0.64) | PARP10PARP15CTNNB1TTRALDH1A1 | |
| SCHEMBL11702647 | 0.87 | PARP10 (0.61) | PARP10PARP15PARP14TNKSTNKS2 | |
| SCHEMBL1852465 | 0.87 | SRD5A2 (0.54) | PARP10CTNNB1TTRALDH1A1KMT2A | |
| SCHEMBL3645145 | 0.85 | SRD5A2 (0.53) | PARP10TTRALDH1A1KMT2ACYP2C19 | |
| SCHEMBL9655279 | 0.85 | TTR (0.53) | PARP10CTNNB1TTRALDH1A1KMT2A | |
| SCHEMBL1854067 | 0.84 | ATM (0.52) | PARP10PARP15PARP14TNKSTNKS2 | |
| SCHEMBL28269929 | 0.84 | HPSE (0.54) | PARP10CTNNB1TTRALDH1A1F10 | |
| SCHEMBL1855090 | 0.83 | HTT (0.53) | PARP10CTNNB1TTRALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4031073-A | Monoazo pigments containing barbituric acid or thio- or imino-derivatives thereof | CIBA-GEIGY CORPORATION (US) | 1977-06-21 | — | — | US | disclosed |