Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRC | Q99895 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 7/20 | 0.43 |
| ▸ | PPARG | P37231 | 7/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.42 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11703273 | 0.89 | MEN1 (0.44) | CTRCMEN1KMT2ARAB9APPARA | |
| SCHEMBL31144647 | 0.82 | CTRC (0.63) | CTRCPPARAPPARGALDH2PTGES | |
| SCHEMBL11854295 | 0.77 | CTRC (0.58) | CTRCPPARAPPARGALDH2PTGES | |
| SCHEMBL11576734 | 0.77 | CTRC (0.58) | CTRCPPARAPPARGALDH2PTGES | |
| SCHEMBL6342298 | 0.77 | CTRC (0.64) | CTRCPPARAPPARGALDH2PTGES | |
| SCHEMBL570688 | 0.77 | CTRC (0.64) | CTRCPPARAPPARGALDH2PTGES | |
| SCHEMBL15903011 | 0.77 | CTRC (0.64) | CTRCPPARAPPARGALDH2PTGES | |
| SCHEMBL4001414 | 0.77 | CTRC (0.64) | CTRCPPARAPPARGALDH2PTGES | |
| SCHEMBL4002165 | 0.77 | CTRC (0.64) | CTRCPPARAPPARGALDH2PTGES | |
| SCHEMBL22828775 | 0.77 | CTRC (0.64) | CTRCPPARAPPARGALDH2PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4035413-A | ANTIALLERGENS, ANTILIPAEMIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1977-07-12 | — | — | US | disclosed |
| US-4013719-A | ANTILIPEMIC, ANTIALLERGEN | CIBA-GEIGY CORPORATION (US) | 1977-03-22 | — | — | US | disclosed |
| US-4000183-A | ANTIALLERGENS AND HYPOLIPIDAEMIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1976-12-28 | — | — | US | disclosed |
| US-4000144-A | HYPOLIPIDAEMIC AGENTS AND ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1976-12-28 | — | — | US | disclosed |
| US-3933835-A | ANTIALLERGENS, HYPOLIPIDAEMIC | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |